Ask Poopreport: What's The Best Medication?
I would be most grateful if you could clarify my following questions:
With regards to treating http://www.mayoclinic.com/health/c-difficile/DS00736 “>Clostridium difficile(C. diff) with http://www.medicinenet.com/vancomycin-oral/article.htm “>Oral Vancomycin, are there any side effects or downside for the Vancomycin coming into contact with the gut and intestinal flora before it gets to the colon, which is where it is needed? Would it make sense for someone to develop an oral Vancomycin product that is delivered to the colon without it contacting the stomach or small intestine?
I noticed that http://www.drugs.com/metronidazole.html “>Metronidazole, which is also used to treat C.diff, can be coated for colonic delivery, but this seems to be used for intestinal http://www.medical-look.com/Parasitic_diseases/Amoebiasis.html “>amoebiasis. I assume it has to be colonically delivered because Metronidazole is absorbed when taken orally, so little to none of it would get to the colon. How does oral Metronidazole work for C.diff if it is absorbed orally?
Another antibiotic is http://www.medicinenet.com/linezolid-oral_tablets/article.htm “>Linezolid, which is also used for C. diff. My question is the same for Linezolid as the questions above. Does it need to be colonically delivered?
Thanks very much,